Sprycel 20mg dose tabets | Blueberrypharmaceuticals


Sprycel 20mg

Description


Sprycel 20mg is a prescription drug which used under the supervision of doctor. Sprycel 20mg is a potent, which contains ATP-competitive tyrosine kinase inhibitor. It is also belonging to second-generation inhibitor of the oncogenic tyrosine kinase BCR-ABL with 325-fold more potency than imatinib and is also able to inhibit imatinib-resistant BCR-ABL mutants.



INDICATION


Sprycel 20mg the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukaemia with resistance or intolerance to prior therapy.Philadelphia chromosome-positive acute lymphoblastic leukaemia with resistance or intolerance to prior therapy.

MECHANISM OF ACTION


Tyrosine kinases are proteins that works as chemical messengers to stimulate cancer cells to develop. Dasatinib inhibits the tyrosine kinases from sending chemical signals which tell the cells to grow.

Dasatinib is a group of drugs called a protein tyrosine kinase inhibitor (TKI).

Side Effects

Anemia
• Skin rash
• Infection
• Nausea
• Dyspnea
• Anorexia
• Arthralgia
• Asthenia
• Constipation
• Dizziness.
Musculoskeletal pain
• Febrile neutropenia
• Thrombocytopenia
• Mucosal inflammation
• Diarrhea
• Headache
• Haemorrhage
• Fatigue
• Pyrexia.

PRECAUTIONS


Sprycel will occur Hypokalaemia, hypomagnesemia, congenital QT interval prolongation, hepatic impairment
• Sprycel should Use with caution in patients who have or may develop prolongation of QT interval.

DRUG — DRUG INTERACTION


Sprycel 20mg combination with CYP3A4 inducers will decrease Dasatinib plasma concentration.
Sprycel 20mg combination with antacids will decrease Dasatinib plasma concentration.
Sprycel 20mg combination with CYP3A4 inhibitors will increase Dasatinib plasma concentration.

MISSED DOSE

In case of missed dose, patients must consult with medical oncologist and follow the regular dosing schedule.

For More Information


Call us : +91–97890 77748

Mail to : info@blueberrypharma.com

Email us : https://blueberrypharma.com/sprycel-20mg.php

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Sprycel 20mg Description : Sprycel 20mg belongs to oral dual BCR/ABL and Src group of tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukaemia (CML). The main aim of Sprycel , are BCRABL, SRC, Ephrin’s and GFR. Sprycel 20mg is a prescription drug which used under the supervision of doctor. Indication : Sprycel 20mg   is indicated for the treatment of adult patients having chronic myeloid leukaemia. Sprycel 20mg is indicated for the treatment of adult patients having acute lymphoblastic leukaemia. DRUG INTERACTION :  Sprycel 20mg combination with CYP3A4 inducers will reduces Dasatinib plasma concentration. Sprycel 20mg combination with antacids will decrease Dasatinib plasma concentration. Sprycel 20mg combination with H2 antagonists/proton pump inhibitors will decrease Dasatinib plasma concentration. PRECAUTION :  Using of Sprycel will results in Tumor lysis syndrome; maintain sufficient hydration and correct ur...
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