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  Xovoltib 30mg

Description :

Xovoltib 30mg is a prescription drugs which is used under the guidance of medical practioners. Xovoltib 30mg belongs to quinazoline and butanamide derivative which acts as a tyrosine kinase inhibitor of epidermal growth factor receptors (ERBB RECEPTORS) and is used in the treatment of metastatic NON-SMALL CELL LUNG CANCER.

Indication :

Xovoltib 30mg is indicated for treatment a certain type of lung cancer (non-small cell lung cancer) which has spread to other parts of the body.

Mechanism :

Xovoltib 30mg dose can blocking the activating sites called tyrosine kinases of various proteins within the cell.By stopping these targets, it will target the cancer will shrink.These proteins are most likely to develop cancer growth when the tumor includes the EGFR gene mutation.

Precautions :

Diarrhae:
Most normal condition for people administrating this medications to have diarrhea. Certain situation this diarrhea can be serious. Severe diarrhea can cause dehydration and renal problems which can sometimes lead to death. During your treatment with Xovoltib 30mg, your doctor should also to treat diarrhea primarily.

Hepatic toxicity :
xovoltib 30mg can worsen liver problems. Doctor will take blood tests to find the liver function before and during your treatment with this medication.

Keratitis:
if patients confirm with suspected keratitis or ulcerative keratitis then stop or discontinue the medications

Interstitial lung disease (ILD) :

Xovoltib 30mg medications can leads to lung and breathing problems. Inform doctor right away about new or worsening lung problems while taking this medications . These problems can involve Dyspnea, cough, or fever.

Bullous and exfoliative skin disorder :

 Xovoltib 30mg can affect skin severely and show redness, rash, and acne. Inform doctor right away if you affected by severe skin reactions such as peeling or blistering.

Embryo-fetal toxicity:
Xovoltib 30mg will cause harm to the foetus when its administrated in pregnancy time.

Drug Interaction :

Xovoltib 30mg Interact with P-gpinducers (carbamazepine, phenytoin, phenobarbital) will decrease exposure to Afatinib.

Concomitant of Xovoltib 30mg with P-gpinhibitors (cyclosporine A, ketoconazole verapamil) exposure will be increased to Afatinib.

Dosage :

Xovoltib the prescribed dose for the treatment of non-small cell lung cancer as follows :
For adult :
The prescribed dose is 40mg taken once per day.
For child dosage :
Ages of 0-17 years is not being studied in children.
The medication should not be used age under 18 years of age
For renal impairment:
prescribed dose is 30mg taken once per day
Take Xovoltib on an empty stomach. Consume the drug 1 hour before or 2 hours after a meal
Avoid cutting or crushing the tablet.

Storage :

Xovoltib 30mg Store at 25℃.
Keep Xovoltib 30mg away from children.

Pregnancy :

When the medication Xovoltib 30mg is administrated to a pregnant woman will harm the foetus.
Pregnancy women should avoid while on treatment with medication Xovoltib 30mg.

Missed Dose :

If the patient is missed to take the dose of Xovoltib 30mg, the missed dose should be skipped and follow the regular dosing schedule. Do not self-medicate. Do not double the dose at the same time.

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