Xgeva 120mg tablet dose| Apple pharmaceuticals

XGEVA 120MG

Xgeva 120mg belongs to novel, fully human IgG2 monoclonal antibody especially to receptor activator of nuclear factor kappa-B ligand (RANKL), restrain bone resorption markers in patients with a difference of metastatic tumors and is being examined in multiple clinical trials for the inhibition and treatment of bone metastases.

XGEVA PRESCRIBED FOR : 

Treatment for patients with increase bone mass in men at more risk for fracture getting androgen deprivation therapy for non-metastatic prostate cancer.
Treatment for patients having to increase bone mass in women at more risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer.

XGEVA DOSAGE: 

For adult :

Osteoporosis : 

60mg SC (subcutaneously) once every 6 months
Injection of drug should be done in upper arm, upper thigh or abdomen 

Giant Cell Tumor of bone :
120mg SC, every 4 weeks with additional 120mg doses on days 8 and 15 of the 1st month treatment
Injection of drug should be done in upper arm, upper thigh or abdomen 

Osteolytic Bone Metastases of Solid Tumors

120mg subcutaneously every 4 weeks
Injection of drug should be done in upper arm, upper thigh or abdomen.

Hypercalcemia :
Dose of 120mg Xgeva tablet given SC, every 4 weeks with additional 120mg doses on days 8 and 15 of the 1st month treatment
Injection of drug should be done in upper arm, upper thigh or abdomen 

Dosage and administration in pediatric :
13 years and older and 45kg or more 

Giant Cell Tumor of bone:
Dose of 120mg Xgeva tablet given SC, every 4 weeks with additional 120mg doses on days 8 and 15 of the 1st month treatment..

PRECAUTION

Xgeva injection may improve the negative effects of immuno-suppressants.Especially the risk for serious infections may be increased. Inform your doctor of any immuno-suppressive drugs you early consume.
Not to receive any type of vaccination without your doctor's consultation while admonishing denosumab.

DRUG INTERACTION

No formal drug-drug interaction with denosumab during trials.
When interacting with some anticancer drug, orthopedic drugs, vaccines will lead to risk of adverse effects can be increased.

MISSED DOSE 

Take the dose immediately before next dose duration, then left off the missed dose and continue regular schedule. Avoid taking double dose at same time. Please consult the doctor for further information.

For More Information :


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