Prolia 60mg tablet | Apple pharmaceuticals

PROLIA 60MG

Description:

Prolia 60mg belongs to novel, fully human IgG2 monoclonal antibody especially to receptor activator of nuclear factor kappa-B ligand (RANKL), restrain bone resorption markers in patients with a difference of metastatic tumors and is being examined in multiple clinical trials for the inhibition and treatment of bone metastases. Chemically, it exists of 2 heavy and 2 light chains. Each light chain contains of 215 amino acids. Each heavy chain contains of 448 amino acids with 4 intramolecular disulfides.

Prolia prescribed For : 

Treatment for patients having postmenopausal women with osteoporosis at high risk for fracture. 
Treatment for patients having to increase bone mass in women at more risk for fracture receiving  adjuvant aromatase inhibitor therapy for breast cancer.
Treatment for patients with increase bone mass in men at more risk for fracture getting androgen deprivation therapy for non-metastatic prostate cancer.

Pharmacological Action of prolia :

Mechanism :

Denosumab linked to RANKL, a protein which is specific for the formation, function and survival of osteoclasts, the cells necessary for bone resorption. Denosumab prohibits osteoclast formation, function and survival hence, reducing bone resorption and raising bone mass and strength of the bone.

Precaution : 

Prolia injection may improve the negative effects of immuno-suppressants. Especially the risk for serious infections may be increased. Inform your doctor of any immuno-suppressive drugs you early consume.
Use in pregnancy only if benefit to mother outweighs risk to fetus. Consult with doctor before the treatment
During Prolia treatment do not breastfeed your infants.

DRUG INTERACTION : 

No formal drug-drug interaction with denosumab during trials.
When interacting with some anticancer drug, orthopedic drugs, vaccines will lead to risk of adverse effects can be increased.

LACTATION :

Prolia 60mg is excreted into human milk is not known. Since possible for severe side effects occurs in nursing infants from Prolia 60mg injection, a decision should be considered that to discontinue nursing or discontinue the drug by giving preference of the importance of the drug to the mother.

For More Information : 

Call us :  +91-9987711567
 
Mail to :  applepharmaceutical@gmail.com

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