Denosumab tablets |Xgeva cost |Prolia side effects || Blueberry Pharmaceuticals

Denosumab


Prolia & Xgeva injection is a trade name of denosumab and which belongs to type of monoclonal antibody.This drug is classified as a “bone-modifying agent”, it works as a RANK ligand (RANKL) inhibitor.
These injections which attach and repairs only certain cells in the body and help to protect healthy cells from destroy.

INDICATION :

It can be indicated for the treatment of Osteoporosis occur in and women (menopause stage) (end of menopause/ change of life), whose have severe problem of fractures increased or who failed to other medication of osteoporosis.Breast cancer in women whose taking certain treatment which make severe their risk of fractures and bone loss in men with prostate cancer.
In adults and some adolescents with giant cell tumor of bone which cannot cured with surgery / surgery is not possible is treated with Denosumab injection.

MECHANISM OF ACTION :

Denosumab is decided to target RANKL (RANK ligand), a protein which act as the main signal to help bone removal/resorption. Some of the bone loss conditions, RANKL overcome the body's natural defense against bone eradication. 



DRUG – DRUG INTERACTION : 

  • No formal drug-drug interaction with denosumab during trials.
  • When interacting with some anticancer drug, orthopedic drugs, vaccines will lead to risk of adverse effects can be increased.

PREGNANCY : 

The Prolia & Xgeva belongs to category C which has no sufficient data in pregnant women to convey any drug analog risk for adverse development outcomes..
The drug in pregnant women is contraindicated for use because it may cause serious risk to the fetus.

CONTRAINDICATIONS : 

Prolia & Xgeva  is contraindicated in :

Hypocalcemia
Pregnancy
Hypersensitivity.

For More Information : 

Call us :   +91-9789077748

Mail us :   info@blueberrypharma.com




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